ORIGINAL ARTICLE
![]()
JOP. J Pancreas (Online) 2008; 9(4):489-492.
Prevalence of Fibrocalculous Pancreatic Diabetes in Chennai in South India
Viswanathan Mohan, Syed Farooq, Mohan Deepa
Madras Diabetes Research Foundation and Dr. Mohan’s Diabetes Specialities Centre, WHO Collaborating Centre for Noncommunicable Diseases Prevention and Control. Chennai, India
ABSTRACT
Context Fibrocalculous pancreatic diabetes is a form of diabetes secondary to chronic pancreatitis found in tropical, developing countries. There is no population based data on prevalence of fibrocalculous pancreatic diabetes.
Objective This paper reports on prevalence of fibrocalculous pancreatic diabetes in Chennai in South India based on the Chennai Urban Rural Epidemiology Study.
Results The prevalence of fibrocalculous pancreatic diabetes is 0.36% (1:276) of all self reported diabetes and 0.019% (1:5,200) of the general population of Chennai.
Conclusion Although the frequency is low, diagnosis of fibrocalculous pancreatic diabetes must be kept in mind in treating diabetic subjects in developing countries as its management would include management of pain, pancreatic enzyme supplements and periodic surveillance for pancreatic malignancy.
| Full text: | HTML format PDF format |
References
Mohan V, Nagalotimath SJ, Yajnik CS, Tripathy BB. Fibrocalculous pancreatic diabetes. Diabetes Metab Rev 1998; 14:153-70. [More details]
Chandak GR, Idris MM, Reddy DN, Bhaskar S, Sriram PV, Singh L. Mutations in the pancreatic secretory trypsin inhibitor gene (PSTI/SPINK1) rather than the cationic trypsinogen gene (PRSS1) are significantly associated with tropical calcific pancreatitis. J Med Genet 2002; 39:347-51. [More details]
Mohan V, Premalatha G, Pitchumoni CS. Tropical chronic pancreatitis: an update. J Clin Gastroenterol 2003; 36:337-46. [More details]
WHO study group report on diabetes mellitus. WHO Technical Report series No.727. Geneva, 1985. [More details]
Alberti KG, Zimmet PZ. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med 1998; 15:539-53. [More details]
Mohan V, Mohan R, Susheela L, Snehalatha C, Bharani G, Mahajan VK, et al. Tropical pancreatic diabetes in South India: heterogeneity in clinical and biochemical profile. Diabetologia 1985; 28:229-32. [More details]
Mohan V, Barman KK, Rajan VS, Chari ST, Deepa R. Natural history of endocrine failure in tropical chronic pancreatitis: a longitudinal follow-up study. J Gastroenterol Hepatol 2005; 20:1927-34. [More details]
Balaji LN, Tandon RK, Tandon BN, Banks PA. Prevalence and clinical features of chronic pancreatitis in Southern India. Int J Pancreatol 1994; 15:29-34. [More details]
Deepa M, Pradeepa R, Rema M, Mohan A, Deepa R, Shanthirani S, Mohan V. The Chennai Urban Rural Epidemiology Study (CURES): study design and methodology (urban component) (CURES-I). J Assoc Physicians India 2003; 51:863-70. [More details]
Geevarghese PJ. Calcific Pancreatitis. Bombay: Varghese Publishing House, 1985. [More details]
Chari ST, Mohan V, Pitchumoni CS, Viswanathan M, Madanagopalan N, Lowenfels AB. Risk of pancreatic carcinoma in tropical calcifying pancreatitis: an epidemiologic study. Pancreas 1994; 9:62-6. [More details]
Augustine P, Ramesh H. Is tropical pancreatitis premalignant? Am J Gastroenterol 1992; 87:1005-8. [More details]
Keywords Calculi; Epidemiology; India; Pancreatitis, Chronic; Prevalence
Correspondence Viswanathan Mohan: drmohans@vsnl.net