JULY 2001: Vol. 2, No. 4 - Table of Contents
EDITORIAL

Outcome and Quality of Life in Chronic Pancreatitis
Talamini G, Bassi C, Butturini G, Falconi M, Casetti L, Gumbs AA, Carrara S, Fantin A, Pederzoli P
Digestive Endoscopy Service, Department of Gastroenterology and Surgical Sciences, University of Verona. Verona, Italy
JOP. J Pancreas (Online) 2001; 2(4):117-123.
REVIEW

"A" is for Amylin and Amyloid in Type 2 Diabetes Mellitus
Hayden MR, Tyagi SC
Camdenton Community Health Center. Camdenton, Missouri. University of Mississippi Medical Center. Jackson, Mississippi, USA
JOP. J Pancreas (Online) 2001; 2(4):124-139.
ORIGINAL ARTICLE

Effect of Treatment with Different Doses of 17-beta-Estradiol on Insulin Receptor Substrate-1
González C, Alonso A, Grueso NA, Díaz F, Esteban MM, Fernández S, Patterson AM
Department of Functional Biology, Physiology Area, University of Oviedo. Oviedo, Spain
JOP. J Pancreas (Online) 2001; 2(4):140-149.
Abstract
SUPPLEMENT

International Symposium on
"HCO3- and Cystic Fibrosis"
San Diego, CA (USA). March 3-5, 2001
GUEST EDITOR: Paul M Quinton (La Jolla, CA, USA)
Preface
Quinton PM
Department of Pediatrics, UCSD School of Medicine. La Jolla, CA, USA
JOP. J Pancreas (Online) 2001; 2(4 Suppl):150-153.
ENZYMES

Bicarbonate-Regulated Soluble Adenylyl Cyclase
Wuttke MS, Buck J, Levin LR
Department of Pharmacology, Weill Cornell Medical College. New York, NY, USA
JOP. J Pancreas (Online) 2001; 2(4 Suppl):154-158.
The Cellular Physiology of Carbonic Anhydrases
Breton S
Program in Membrane Biology/Renal Unit, Massachusetts General Hospital. Charlestown, MA, USA. Department of Medicine, Harvard Medical School. Boston, MA, USA
JOP. J Pancreas (Online) 2001; 2(4 Suppl):159-164.
Carbonic Anhydrase: In the Driver’s Seat for Bicarbonate Transport
Sterling D, Reithmeier RAF, Casey JR
Membrane Transport Group and CIHR Group in Molecular Biology of Membrane Proteins, Department of Physiology, University of Alberta. Edmonton, Canada. CIHR Group in Membrane Biology, Department of Medicine, University of Toronto. Toronto, Canada
JOP. J Pancreas (Online) 2001; 2(4 Suppl):165-170.
CARRIER MEDIATED TRANSPORT

Regulation of Na+-Independent Cl-/HCO3- Exchangers by pH
Alper SL, Chernova MN, Stewart AK
Departments of Medicine and Cell Biology, Harvard Medical School; Molecular Medicine and Renal Units, Beth Israel Deaconess Medical Center. Boston, MA, USA
JOP. J Pancreas (Online) 2001; 2(4 Suppl):171-175.
Sodium-coupled bicarbonate transporters
Boron WF
Department of Cell and Molecular Physiology, Yale University School of Medicine, New Haven, CT. USA
JOP. J Pancreas (Online) 2001; 2(4 Suppl):176-181.
The Electrogenic Na+/HCO3– Cotransporter, NBC
Romero MF
Department of Physiology and Biophysics, Department of Pharmacology, Case Western Reserve University School of Medicine. Cleveland, OH, USA
JOP. J Pancreas (Online) 2001; 2(4 Suppl):182-191.
REGULATION AND CONTROL OF HCO3- TRANSPORT

Pancreatic Ductal Bicarbonate Secretion: Past, Present and Future
Ishiguro H, Naruse S, San Román JI, Case M, Steward MC
Departments of Internal Medicine II and Human Nutrition, Nagoya University School of Medicine. Nagoya, Japan, School of Biological Sciences, University of Manchester. United Kingdom. Departamento de Fisiología y Farmacología, Universidad de Salamanca. Salamanca, Spain
JOP. J Pancreas (Online) 2001; 2(4 Suppl):192-197.
150 mM HCO3- - How Does the Pancreas Do It? Clues from Computer Modelling of the Duct Cell
Sohma Y, Gray MA, Imai Y, Argent BE
Department of Physiology, Osaka Medical College. Takatsuki, Osaka, Japan. Department of Physiological Sciences, University Medical School. Newcastle upon Tyne, UK
JOP. J Pancreas (Online) 2001; 2(4 Suppl):198-202.
Coordination of Pancreatic HCO3- Secretion by Protein-Protein Interaction between Membrane Transporters
Lee MG, Ahn W, Lee JA, Kim JY, Choi JY, Moe OW, Milgram SL, Muallem S, Kim KH
Department of Pharmacology, Yonsei University College of Medicine. Seoul, Korea. Department of Physiology and Department of Internal Medicine, University of Texas, Southwestern Medical Center. Dallas, Texas (USA). Department of Cell and Molecular Physiology, University of North Carolina. Chapel Hill, North Carolina (USA)
JOP. J Pancreas (Online) 2001; 2(4 Suppl):203-206.
Functional Interactions of HCO3- with Cystic Fibrosis Transmembrane Conductance Regulator
Gray MA, O’Reilly C, Winpenny J, Argent B
Department of Physiological Sciences, University Medical School. Newcastle upon Tyne, United Kingdom. Biomedical Imaging Group, Department of Physiology, University of Massachusetts Medical Centre. Worcester, MA, USA. School of Health Sciences, University of Sunderland. Sunderland, United Kingdom
JOP. J Pancreas (Online) 2001; 2(4 Suppl):207-211.
Selective Activation of Cystic Fibrosis Transmembrane Conductance Regulator Cl- and HCO3- Conductances
Reddy MM, Quinton PM
Department of Pediatrics, UCSD School of Medicine. La Jolla, CA, USA
JOP. J Pancreas (Online) 2001; 2(4 Suppl):212-218.
Microelectrode and Impedance Analysis of Anion Secretion in Calu-3 Cells
Tamada T, Hug MJ, Frizzell RA, Bridges RJ
Department of Cell Biology and Physiology, University of Pittsburgh School of Medicine. Pittsburgh, PA, USA. Institut für Physiologie, Westfälische Wilhelms-Universität Münster. Münster, Germany
JOP. J Pancreas (Online) 2001; 2(4 Suppl):219-228.
Cystic Fibrosis Transmembrane Conductance Regulator and H+ Permeability in Regulation of Golgi pH
Machen TE, Chandy G, Wu M, Grabe M, Moore HP
Department of Molecular and Cell Biology and Department of Physics, University of California. Berkeley, CA, USA
JOP. J Pancreas (Online) 2001; 2(4 Suppl):229-236.
HCO3- AND CYSTIC FIBROSIS

Impaired Pancreatic Ductal Bicarbonate Secretion in Cystic Fibrosis
Soleimani M
Department of Medicine, University of Cincinnati, and Veterans Affairs Medical Center at Cincinnati, Cincinnati, OH, USA
JOP. J Pancreas (Online) 2001; 2(4 Suppl):237-242.
Cl--Dependent HCO3- Transport by Cystic Fibrosis Transmembrane Conductance Regulator
Choi JY, Lee MG, Ko S, Muallem S
Department of Physiology, UT Southwestern Medical Center. Dallas, TX, USA. Department of Pharmacology, Yonsei University. Seoul, Korea
JOP. J Pancreas (Online) 2001; 2(4 Suppl):243-246.
Na+/HCO3- Cotransport in Normal and Cystic Fibrosis Intestine
Seidler U, Bachmann O, Jacob P, Christiani S, Blumenstein I, Rossmann H
1st Department of Medicine, University of Tübingen. Tübingen, Germany
JOP. J Pancreas (Online) 2001; 2(4 Suppl):247-256.
Bicarbonate Secretion in the Murine Gallbladder - Lessons for the Treatment of Cystic Fibrosis
Cuthbert AW
Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Hill's Road. Cambridge, United Kingdom
JOP. J Pancreas (Online) 2001; 2(4 Suppl):257-262.
Intestinal Bicarbonate Secretion in Cystic Fibrosis Mice
Clarke LL, Stien X, Walker NM
Dalton Cardiovascular Research Center and Department of Biomedical Sciences, University of Missouri. Columbia, MO, USA
JOP. J Pancreas (Online) 2001; 2(4 Suppl):263-267.
Duodenal Intracellular Bicarbonate and the ‘CF Paradox’
Kaunitz JD, Akiba Y
Greater Los Angeles Veterans Affairs Healthcare System, CURE: Digestive Diseases Research Center, and Department of Medicine, School of Medicine, University of California Los Angeles, Los Angeles, CA, USA. 1Keio University School of Medicine. Shinjuku-ku, Tokyo, Japan
JOP. J Pancreas (Online) 2001; 2(4 Suppl):268-273.
pH Regulation and Bicarbonate Transport of Isolated Porcine Submucosal Glands
Hug MJ, Bridges RJ
Institut für Physiologie, Westfälische Wilhelms,Universität Münster. Münster, Germany. Department of Cell Biology and Physiology, University of Pittsburgh School of Medicine. Pittsburgh, PA, USA
JOP. J Pancreas (Online) 2001; 2(4 Suppl):274-279.
HCO3- Transport in Relation to Mucus Secretion from Submucosal Glands
Joo NS, Krouse ME, Wu JV, Saenz Y, Jayaraman S, Verkman A, Wine JJ
Cystic Fibrosis Research Laboratory, Stanford University. Stanford, CA, USA. Ethicon Endo-Surgery, Inc. Cincinnati, OH, USA. Departments of Medicine and Physiology, Cardiovascular Research Institute, University of California. San Francisco, CA, USA
JOP. J Pancreas (Online) 2001; 2(4 Suppl):280-284.
Detection of Cl--HCO3- and Na+-H+ Exchangers in Human Airways Epithelium
Al-Bazzaz FJ, Hafez N, Tyagi S, Gailey CA, Toofanfard M, Alrefai WA, Nazir TM, Ramaswamy K, Dudeja PK
Department of Medicine, University of Illinois at Chicago and VA Chicago Health Care System. West Side Division. Chicago, Illinois (USA)
JOP. J Pancreas (Online) 2001; 2(4 Suppl):285-290.
cAMP Stimulation of HCO3- Secretion Across Airway Epithelia
Welsh MJ, Smith JJ
Howard Hughes Medical Institute and Departments of Internal Medicine and Pediatrics, University of Iowa College of Medicine. Iowa City, IA, USA
JOP. J Pancreas (Online) 2001; 2(4 Suppl):291-293.
Regulation and Functional Significance of Airway Surface Liquid pH
Coakley RD, Boucher RC
The Cystic Fibrosis/Pulmonary Research and Treatment Center, University of North Carolina at Chapel Hill. Chapel Hill, North Carolina, USA
JOP. J Pancreas (Online) 2001; 2(4 Suppl):294-300.